Biochemie
Topics and focal points
In our laboratory, we use cells with an artificially expanded genetic code to produce proteins with new properties. In particular, we are interested in a family of enzymes known as sirtuins, which play a central role in a variety of cellular processes. We are using our methods to develop new analytical procedures to understand the function and regulation of these enzymes.
Equipment
The laboratory of the Biochemistry Department is equipped with modern devices for the production (in bacteria and mammalian cells), purification and analysis of proteins. It also has standard equipment for molecular biology work.
Selected publications
- Neumann-Staubitz P., Lammers M., Neumann H. (2021) Genetic Code Expansion Tools to Study Lysine Acylation. Adv Biol e2100926.
- Spinck M., Neumann-Staubitz P., Ecke M., Gasper R., Neumann H. (2020) Evolved, Selective Erasers of Distinct Lysine Acylations. Angew Chem Int Ed Engl 59, 11142-11149.
- Neumann H., Neumann-Staubitz P., Witte A., Summerer D. (2018) Epigenetic chromatin modification by amber suppression technology. Curr Opin Chem Biol 45, 1-9.
Contact us
Prof. Dr. Heinz Neumann
Communication
Stephanstrasse 7
64295 Darmstadt
Office: B15, 1.06
+49.6151.533-68203
heinz.neumann@h-da.de
Own website
ORCID: 0000-0001-9657-1913