Prof. Dr. Franz-Josef Meyer-Almes
Lehrgebiet
Biochemie
Sprechstunde
nach Vereinbarung
- Forschungsbeauftragte/r
- Promotionsbeauftragte/r
- CIO-Gremium (Mitglied)
- Fachbereichsrat (Mitglied Stellvertreter/in)
- Brandschutzhelfer/in
- zfe-Mitglied
Details zur Person
SHORT BIOGRAPHY
1986–1991: Studied Chemistry at Georg August University of Göttingen.
1991–1994: Doctoral research at the Max Planck Institute for Biophysical Chemistry under the supervision of Prof. Dr. M. Eigen.
1995–2001: Project Manager at EVOTEC AG in Hamburg and Düsseldorf.
2001–2004: Laboratory Head in Drug Discovery at Bayer HealthCare AG in Wuppertal.
Since 2004: Professor of Biochemistry at Darmstadt University of Applied Sciences.
Author of more than 90 scientific publications, primarily in the fields of histone deacetylase (HDAC) inhibitor development and physicochemical investigations of protein–ligand interactions.
RESEARCH AND TEACHING AREAS
- Sustainable drug design and synthesis
- Thermodynamics and kinetics of protein–ligand interactions
- Reaction mechanisms and chemical kinetics
- Development of biological assay systems
- High-throughput drug discovery
- Fluorescence spectroscopy
News
2020-2023
The Meyer-Almes Research Group is participating in the new LOEWE-Schwerpunkt "Transiente Bindungstaschen" in collaboration with TU Darmstadt and Goethe University Frankfurt. The research group focuses on the modulation of human histone deacetylases (HDACs), particularly HDAC4, which plays a central role in the pathogenesis of Huntington’s disease and various types of cancer. Using specialized assays, the group aims to investigate the binding kinetics of drug candidates to HDACs in order to identify ligands with distinctive binding mechanisms.
Biophysics in Drug Discovery, Straßburg 2016
Doctoral student Christian Meyners was the only speaker at the conference who had not yet earned a doctorate. He presented findings from his doctoral research on the topic: “Combining Binding Thermodynamics and Kinetic Binding Mechanisms to Assess the Selectivity of Inhibitors of Histone Deacetylase-Like Amidohydrolases.”
Poster award of the Biophysical Society
The poster presented by Andreas Krämer, a doctoral student in the Meyer-Almes Research Group, received an award at the 10th European Biophysics Congress 2015 in Dresden. It was ranked among the top 10 out of 1,000 submitted contributions.
Anton Frühauf’s Doctorate
On May 4, 2026, Anton Frühauf successfully defended his doctoral dissertation entitled “Development of Specific Inhibitors of Human Histone Deacetylase 4” in the Department of Chemistry at TU Darmstadt.
Kontakt
Kommunikation
Stephanstraße 7
64295 Darmstadt
Büro: B15, 1.05
+49.6151.533-68406
franz-josef.meyer-almes@h-da.de
Details zur Person
ORCID: 0000-0002-1001-3249
Lehrgebiet
Biochemie
1
Sprechstunde
nach Vereinbarung